Wednesday, January 14, 2009

New breakthroughs in the treatment of heart disease

Recently, the Singapore Medical researchers claim that they have been successful in human bone marrow cells into myocardial cells, the technology in the field of heart disease treatment breakthrough means that tens of millions of heart disease in addition to heart transplantation, the will be able to have a new choice.
To participate in the study of cardiac and thoracic surgeon莱达厄尔奥克雷
, Said: "Our studies have shown that bone marrow cells can survive in the heart. In fact, we can bone marrow into cardiomyocytes, so that recovery of myocardial damage."
奥克雷and two other hospitals in the National University of Singapore researchers together on human bone marrow stem cells (with the formation of the new organization's ability) to conduct genetic modification, and to give them with the characteristics of human heart cells. Last year, they will of these genetically modified cells implanted in mice in vivo. Dr.奥克雷hope that within one year of clinical study of patients with heart disease to start.
奥克雷that myocardial cells between the exchange of a very complicated system, which, once damaged, such as a heart attack, it will lose its function of myocardial cells become useless scar tissue. Therefore no longer be able to shrink the heart beating, losing its "pump" role, which is ultimately a lot of patients with heart failure without the real reason for governance.
The world in 1995 due to heart disease deaths to 15 million, accounting for the total global death toll of 30%. World Health Organization (WHO) estimates that by 2020, this proportion will rise to 40%.
At present, for the treatment of heart disease include: long-term drug therapy, temporary equipment intervention therapy (artificial heart, in vitro blood pump, etc.), and heart transplantation. Heart transplant the main problems is the lack of suitable organ donors.奥克雷said Dr.
In the 10 who are in need of heart transplant patients, can find a suitable organ donation is less than 1 person.
In Paris and Los Angeles completed the other two clinical trials, researchers succeeded in skeletal muscle cells into patients with heart meat inside, used to help repair damaged myocardium. But奥克雷that skeletal muscle cells, it is very difficult jerky sampling, and must be cultured in the laboratory a few days before they can implant the heart. In contrast, more abundant source of bone marrow cells. For example, when surgeons carrying out heart bypass surgery in patients with open chest, the ribs in the bone marrow can be collected ,4-6 hours can be converted into myocardial cells, and then injected into the heart, the surgery ended.

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