Gene deletion can lead to heart disease

Ping'an Hospital of Zhengzhou City Professor Wang Xuehai a latest research results confirm that: gene deletion can lead to congenital heart disease. A few days ago, to participate in identification of experts believe that "the results of the study reached the international advanced level."
China-born babies each year, approximately 150,000 newborns suffer from congenital heart disease, of which one third due to lack of timely diagnosis and treatment of children and mortality. Critically ill children with congenital heart disease in conotruncal heart defect accounts for about 80%. Ping'an Hospital of Zhengzhou City,丁主任, applications such as Professor Wang Xuehai experimental embryology and molecular biology technology, the Chinese tetralogy of Fallot children with genes related to basic research, first reported the Chinese people tetralogy integrated gene in patients with 22q11 microdeletion incidence rate of 24.24 percent and for the first time the use of experimental embryology and molecular biology technology research conotruncal defect-related genes, were also reported for the first time the Chinese people and the Williams Syndrome supravalvular aortic stenosis in patients with elastin gene and LIM kinase 1 gene deletions.

Experts point out that the results of the study will clarify the causes of congenital heart disease and pathogenesis, and for the early diagnosis and pathogenesis of congenital heart block, have a positive significance.